The Abolition Amendment was designed to be passed and ratified at the federal level, thereby ending slavery and emancipating all animals throughout the United States of America. But with a simple modification of the text, the Abolition Amendment can also be enacted at the state level. The Humane Party expressly encourages activists to pursue abolition at the state level, even before sufficient numbers have been attained to achieve victory at the national level. However, as the Compromise of 1820 (“Missouri Compromise”) marks its 200th anniversary, it is worth examining a concern associated with the state-by-state approach.